Progressive Lens Luxation

Sealyham Terriers suffer from a painful eye condition known as Primary Lens Luxation (PLL). In PLL the lens is displaced from its normal position due to a weakening of the ligaments holding it in place.

Normally the lens is suspended between the iris and the retina, held in position by the lens zonules and the adjacent vitreous. There can be partial (sub-luxation) or complete displacement (luxation) of the lens from its normal site, either forward into the anterior chamber of the eye (in front of the pupil) or backward into the vitreous.

Forward (anterior) lens luxation may cause an increase in pressure within the eye (glaucoma), which if untreated leads to blindness. With an anterior luxation the dog may show signs of intense pain (rubbing, pawing at the eye), or visual impairment associated with glaucoma. Alternatively, the dog may show no clinical signs and the veterinary surgeon may observe an ocular abnormality during a routine examination.

PLL has not been recorded in Cesky Terriers in the UK, but the breed club has nevertheless recommended that all breeding stock is eye-tested under the KC/BVA scheme.

The exciting news is that the gene mutation responsible for PLL in the Sealyham Terrier has now been found. It is now possible for owners to test their dog's PLL status by using a simple cheek swab. All details are available on the Animal Health Trust website.

Researchers at the Animal Health Trust are carrying out a project in conjuction with the Cesky Terrier Club to ascertain whether PLL is present in the breed. If no carriers or affecteds are found we can be fairly certain that our dogs have not inherited this disease from their Sealyham ancestors.
Health